Scientific article
Open access

The corpus callosum : white matter or terra incognita

Published inThe British journal of radiology, vol. 84, no. 997, p. 5-18
Publication date2011-01
First online date2011-01-01

The corpus callosum is the largest white matter structure in the brain, consisting of 200-250 million contralateral axonal projections and the major commissural pathway connecting the hemispheres of the human brain. The pathology of the corpus callosum includes a wide variety of entities that arise from different causes such as congenital, inflammatory, tumoural, degenerative, infectious, metabolic, traumatic, vascular and toxic agents. The corpus callosum, or a specific part of it, can be affected selectively. Numerous pathologies of the corpus callosum are encountered during CT and MRI. The aim of this study is to facilitate a better understanding and thus treatment of the pathological entities of the corpus callosum by categorising them according to their causes and their manifestations in MR and CT imaging. Familiarity with its anatomy and pathology is important to the radiologist in order to recognise its disease at an early stage and help the clinician establish the optimal therapeutic approach.

  • Brain Diseases / pathology
  • Corpus Callosum / anatomy & histology
  • Corpus Callosum / pathology
  • Humans
  • Magnetic Resonance Imaging / methods
  • Nerve Tissue / pathology
  • Predictive Value of Tests
  • Tomography, X-Ray Computed / methods
Citation (ISO format)
FITSIORI, Aikaterini et al. The corpus callosum : white matter or terra incognita. In: The British journal of radiology, 2011, vol. 84, n° 997, p. 5–18. doi: 10.1259/bjr/21946513
Main files (1)
Article (Published version)
ISSN of the journal0007-1285

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