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Scientific article
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674 Cases of Late Postoperative Intraocular Lens Opacification of a Hydrophilic-Hydrophobic Acryl Intraocular Lens in Switzerland and Retrospective Opacification Risk Factor Assessment of 212 Cases

Other title674 Fälle von später, postoperativer Intraokularlinsentrübungen einer hydrophilen-hydrophoben Acryl-Linse in der Schweiz und retrospektives Eintrübungsrisiko-Einschätzung von 212 Fällen
Published inKlinische Monatsblätter für Augenheilkunde, vol. 240, no. 4, p. 440-445
Publication date2023-04-25
First online date2023-04-25
Abstract

Purpose : To report the prevalence of late postoperative opacification of a hydrophilic and hydrophobic acrylic intraocular lens (IOL) and to assess the risk factors in a subset of 212 eyes of patients referred to the University Eye Department in Basel, Switzerland.

Design : Retrospective case series.

Methods : A survey was performed at all large ophthalmological clinics in Switzerland regarding exchanged Lentis LS-502-1 lenses, and the number of affected eyes was counted. Moreover, consecutive patients who were referred to a tertiary clinic between September 2015 and November 2016 with Lentis LS-502-1 opacification were investigated. Peri- and postoperative charts, medical history, and topical and systemic medications were assessed.

Results : A total of 674 opacified Lentis LS-502-1 lenses have been reported in Switzerland, and 212 consecutive eyes of 182 patients were included in the study. All IOLs had a similar pattern of opacification with a yellowish, diffuse appearance, and most of them showed a small, paracentral, roundish area that was less affected or not at all. Arterial hypertension (73%), hypercholesterolemia (34%), and diabetes (21%) were the main associated systemic diseases, and statins (34%) and betablockers (34%) were the main treatments used.

Conclusions : The prevalence of IOL opacification was 9.9%. No associated systemic eye disease or medications could be detected, which was implicated in the opacification process. The reason for opacification remains unclear, but it seems to be unrelated to the patientʼs state; therefore, it is attributed to primary calcification.

eng
Keywords
  • Capsule Opacification / etiology
  • Humans
  • Lens Implantation, Intraocular / adverse effects
  • Lenses, Intraocular / adverse effects
  • Phacoemulsification
  • Postoperative Complications / epidemiology
  • Postoperative Complications / etiology
  • Retrospective Studies
  • Risk Factors
  • Switzerland / epidemiology
Citation (ISO format)
AMON, Tabea et al. 674 Cases of Late Postoperative Intraocular Lens Opacification of a Hydrophilic-Hydrophobic Acryl Intraocular Lens in Switzerland and Retrospective Opacification Risk Factor Assessment of 212 Cases. In: Klinische Monatsblätter für Augenheilkunde, 2023, vol. 240, n° 4, p. 440–445. doi: 10.1055/a-2013-1478
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ISSN of the journal0023-2165
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