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Scientific article
English

Long term results of non-surgical, exclusive strontium-/yttrium-90 beta-irradiation of pterygia

Published inRadiotherapy and oncology, vol. 74, no. 1, p. 25-29
Publication date2005-01
Abstract

Background and purpose: To evaluate long term results and to demonstrate safety and efficacy of non-surgical, exclusive strontium-/ yttrium-90 beta irradiation of non-operated pterygia.

Patients and methods: Between March 1977 and April 1999, 43 patients with 54 primary pterygia were treated with an exclusive strontium-/yttrium-90 beta-irradiation up to a total dose of 50 Gy divided in four fractions with one week apart. All patients were referred from the same ophthalmologist. The average follow-up were 112(G88 months (range, 12–321 months), median 96 months.

Results: The patients were referred with early symptomatic manifestations of pterygia with a mean horizontal diameter of 1.6G0.7 mm (range, 0.5–4.5 mm), which shrank to a mean diameter of 0.9G0.6 mm (range, 0–2.5 mm) after irradiation (P!0.005). There was a reduction of size in every pterygium, none of the 54 pterygia developed a recurrent growth and there were no patient with any late side effect. Following the strontium-/yttrium-90 application the process came up with an obliteration of the vessels, which resulted in a grey, thin and avascular pannus.

Conclusions: Strontium-/yttrium-90 beta-irradiation as an exclusive, non-surgical treatment for early pterygia provides a significant reduction of the size of the irradiated pterygia, is a safe and effective therapy to prevent a recurrence and can be performed without late side effects.

eng
Keywords
  • Adult
  • Aged
  • Female
  • Follow-Up Studies
  • Humans
  • Male
  • Middle Aged
  • Pterygium / pathology
  • Pterygium / radiotherapy
  • Radiation Injuries
  • Strontium Radioisotopes / therapeutic use
  • Treatment Outcome
  • Yttrium Radioisotopes / therapeutic use
Affiliation Not a UNIGE publication
Citation (ISO format)
PAJIC, Bojan, GREINER, Richard H. Long term results of non-surgical, exclusive strontium-/yttrium-90 beta-irradiation of pterygia. In: Radiotherapy and oncology, 2005, vol. 74, n° 1, p. 25–29. doi: 10.1016/j.radonc.2004.08.022
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Article (Published version)
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ISSN of the journal0167-8140
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