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Scientific article
English

SPILF update on bacterial arthritis in adults and children

Published inInfectious diseases now, vol. 53, no. 4, 104694
Publication date2023-06
Abstract

In 2020 the French Society of Rhumatology (SFR) published an update of the 1990 recommendations for management of bacterial arthritis in adults. While we (French ID Society, SPILF) totally endorse this update, we wished to provide further information about specific antibiotic treatments. The present update focuses on antibiotics with good distribution in bone and joint. It is important to monitor their dosage, which should be maximized according to PK/PD parameters. Dosages proposed in this update are high, with the optimized mode of administration for intravenous betalactams (continuous or intermittent infusion). We give tools for the best dosage adaptation to conditions such as obesity or renal insufficiency. In case of enterobacter infection, with an antibiogram result "susceptible for high dosage", we recommend the requesting of specialized advice from an ID physician. More often than not, it is possible to prescribe antibiotics via the oral route as soon as blood cultures are sterile and clinical have symptoms shown improvement. Duration of antibiotic treatment is 6 weeks for Staphylococcus aureus, and 4 weeks for the other bacteria (except for Neisseria: 7 days).

eng
Keywords
  • Adults
  • Antibiotic treatment
  • Bacterial arthritis
  • Children
  • Guidelines
Citation (ISO format)
STAHL, Jean-Paul et al. SPILF update on bacterial arthritis in adults and children. In: Infectious diseases now, 2023, vol. 53, n° 4, p. 104694. doi: 10.1016/j.idnow.2023.104694
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ISSN of the journal2666-9919
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Technical informations

Creation10/10/2023 8:45:50 AM
First validation02/14/2024 8:18:42 AM
Update time02/14/2024 8:18:42 AM
Status update02/14/2024 8:18:42 AM
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