Direct and indirect regulation of Pom1 cell size pathway by the protein phosphatase 2C Ptc1

Gerganova, Veneta; Bhatia, Payal; Vincenzetti, Vincent; Martin, Sophie

doi:10.1091/mbc.E20-08-0508

Scientific article

English

Direct and indirect regulation of Pom1 cell size pathway by the protein phosphatase 2C Ptc1

ContributorsGerganova, Veneta; Bhatia, Payal; Vincenzetti, Vincent; Martin, Sophie

Published inMolecular biology of the cell, vol. 32, no. 8, p. 703-711

Publication date2021-04-15

Abstract

This article probes the function of the type 2C phosphatase Ptc1 and shows it participates in cell size regulation through the Pom1 kinase. Ptc1 can dephosphorylate Pom1 but modulates its localization indirectly, indicating direct and indirect roles of this protein phosphatase.

Affiliation entities

Not a UNIGE publication

Funding

Swiss National Science Foundation - Cell polarization in response to intra- and extracellular cues in fission yeast [138177]

Citation (ISO format)

GERGANOVA, Veneta et al. Direct and indirect regulation of Pom1 cell size pathway by the protein phosphatase 2C Ptc1. In: Molecular biology of the cell, 2021, vol. 32, n° 8, p. 703–711. doi: 10.1091/mbc.E20-08-0508

Article (Published version)

CC BY-NC-SA-3.0

Identifiers

PID : unige:174550
DOI : 10.1091/mbc.E20-08-0508
PMID : 33625871
PMCID : PMC8108516

Additional URL for this publicationhttps://www.molbiolcell.org/doi/10.1091/mbc.E20-08-0508

Journal ISSN1059-1524

41views

34downloads

Creation30/01/2024 16:57:55

First validation31/01/2024 16:20:55

Update time31/01/2024 16:20:55

Status update31/01/2024 16:20:55

Last indexation01/11/2024 07:22:51

Archive ouverte UNIGE

Direct and indirect regulation of Pom1 cell size pathway by the protein phosphatase 2C Ptc1

This article probes the function of the type 2C phosphatase Ptc1 and shows it participates in cell size regulation through the Pom1 kinase. Ptc1 can dephosphorylate Pom1 but modulates its localization indirectly, indicating direct and indirect roles of this protein phosphatase.

Technical informations