DYRK kinase Pom1 drives F-BAR protein Cdc15 from the membrane to promote medial division

Bhattacharjee, Rahul; Mangione, MariaSanta C.; Wos, Marcin; Chen, Jun-Song; Snider, Chloe E.; Roberts-Galbraith, Rachel H.; McDonald, Nathan A.; Presti, Libera Lo; Martin, Sophie; Gould, Kathleen L.

doi:10.1091/mbc.E20-01-0026

Scientific article

English

DYRK kinase Pom1 drives F-BAR protein Cdc15 from the membrane to promote medial division

ContributorsBhattacharjee, Rahul; Mangione, MariaSanta C.; Wos, Marcin

; Chen, Jun-Song; Snider, Chloe E.; Roberts-Galbraith, Rachel H.; McDonald, Nathan A.; Presti, Libera Lo; Martin, Sophie

; Gould, Kathleen L.

Published inMolecular biology of the cell, vol. 31, no. 9, p. 917-929

Publication date2020-04-15

Abstract

Phosphorylation by the DYRK kinase Pom1 is one of two major signals for proper division site placement in Schizosaccharomyces pombe. Pom1 phosphorylation of F-BAR protein Cdc15 inhibits its membrane and protein binding, thus inhibiting scaffolding of the cytokinetic ring and preventing mislocalized division.

Affiliation entities

Not a UNIGE publication

Funding

NIGMS NIH HHS - [F31 GM119252]
Swiss National Science Foundation - Mechanisms of cell polarization in response to external cues [155944]

Citation (ISO format)

BHATTACHARJEE, Rahul et al. DYRK kinase Pom1 drives F-BAR protein Cdc15 from the membrane to promote medial division. In: Molecular biology of the cell, 2020, vol. 31, n° 9, p. 917–929. doi: 10.1091/mbc.E20-01-0026

Article (Published version)

CC BY-NC-SA-3.0

Identifiers

PID : unige:174546
DOI : 10.1091/mbc.E20-01-0026
PMID : 32101481
PMCID : PMC7185970

Additional URL for this publicationhttps://www.molbiolcell.org/doi/10.1091/mbc.E20-01-0026

Journal ISSN1059-1524

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DYRK kinase Pom1 drives F-BAR protein Cdc15 from the membrane to promote medial division

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