Enhancing Selectivity of Protein Biopharmaceuticals in Ion Exchange Chromatography through Addition of Organic Modifiers
Contributeurs/tricesDuivelshof, Bastiaan; Bouvarel, Thomas ; Pirner, Sebastian ; Larraillet, Vincent; Knaupp, Alexander; Koll, Hans; D'Atri, Valentina ; Guillarme, Davy
Publié dansInternational journal of molecular sciences, vol. 24, no. 23, p. 16623
Date de publication2023-11-22
Date de mise en ligne2023-11-22
Résumé
Mots-clés
- Fab fragment
- Bispecific antibody
- Ion exchange chromatography
- Monoclonal antibody
- Organic modifier
- Salt gradient
- Salt-mediated pH gradient
Structure d'affiliation
Groupe de recherche
Financement
- Roche Diagnostics GmbH -
Citation (format ISO)
DUIVELSHOF, Bastiaan et al. Enhancing Selectivity of Protein Biopharmaceuticals in Ion Exchange Chromatography through Addition of Organic Modifiers. In: International journal of molecular sciences, 2023, vol. 24, n° 23, p. 16623. doi: 10.3390/ijms242316623
Fichiers principaux (1)
Article (Published version)
Identifiants
- PID : unige:174031
- DOI : 10.3390/ijms242316623
- PMID : 38068945
- PMCID : PMC10706461
URL commercialhttps://www.mdpi.com/1422-0067/24/23/16623
ISSN du journal1422-0067