Scientific article

Practical guidelines of the eottd for pathological and genetic diagnosis of hydatidiform moles

Published inVirchows Archiv, vol. 484, no. 3, p. 401-422
  • Published erratum : Bartosch C, Nadal A, Braga AC, Salerno A, Rougemont AL, Van Rompuy AS, Fitzgerald B, Joyce C, Allias F, Maher GJ, Turowski G, Tille JC, Alsibai KD, Van de Vijver K, McMahon L, Sunde L, Pyzlak M, Downey P, Wessman S, Patrier S, Kaur B, Fisher R. Correction to: Practical guidelines of the EOTTD for pathological and genetic diagnosis of hydatidiform moles. Virchows Arch. 2024 Mar;484(3):539-548.
  • DOI : 10.1007/s00428-023-03715-2
  • PMID : 38421406
Publication date2023-10-19
First online date2023-10-19

Hydatidiform moles are rare and thus most pathologists and geneticists have little experience with their diagnosis. It is important to promptly and correctly identify hydatidiform moles given that they are premalignant disorders associated with a risk of persistent gestational trophoblastic disease and gestational trophoblastic neoplasia. Improvement in diagnosis can be achieved with uniformization of diagnostic criteria and establishment of algorithms. To this aim, the Pathology and Genetics Working Party of the European Organisation for Treatment of Trophoblastic Diseases has developed guidelines that describe the pathological criteria and ancillary techniques that can be used in the differential diagnosis of hydatidiform moles. These guidelines are based on the best available evidence in the literature, professional experience and consensus of the experts' group involved in its development.

  • Diagnosis
  • Genetics
  • Genotyping
  • Guidelines
  • Hydatidiform moles
  • Pathology
Citation (ISO format)
BARTOSCH, Carla et al. Practical guidelines of the eottd for pathological and genetic diagnosis of hydatidiform moles. In: Virchows Archiv, 2023, vol. 484, n° 3, p. 401–422. doi: 10.1007/s00428-023-03658-8
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Article (Published version)
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ISSN of the journal0945-6317

Technical informations

Creation12/26/2023 1:38:52 PM
First validation01/04/2024 10:19:30 AM
Update time06/12/2024 7:32:38 AM
Status update06/12/2024 7:32:38 AM
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