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Scientific article
Review
English

Practical guidelines of the eottd for pathological and genetic diagnosis of hydatidiform moles

Published inVirchows Archiv, vol. 484, no. 3, p. 401-422
Errata
  • Published erratum : Bartosch C, Nadal A, Braga AC, Salerno A, Rougemont AL, Van Rompuy AS, Fitzgerald B, Joyce C, Allias F, Maher GJ, Turowski G, Tille JC, Alsibai KD, Van de Vijver K, McMahon L, Sunde L, Pyzlak M, Downey P, Wessman S, Patrier S, Kaur B, Fisher R. Correction to: Practical guidelines of the EOTTD for pathological and genetic diagnosis of hydatidiform moles. Virchows Arch. 2024 Mar;484(3):539-548.
  • DOI : 10.1007/s00428-023-03715-2
  • PMID : 38421406
Publication date2023-10-19
First online date2023-10-19
Abstract

Hydatidiform moles are rare and thus most pathologists and geneticists have little experience with their diagnosis. It is important to promptly and correctly identify hydatidiform moles given that they are premalignant disorders associated with a risk of persistent gestational trophoblastic disease and gestational trophoblastic neoplasia. Improvement in diagnosis can be achieved with uniformization of diagnostic criteria and establishment of algorithms. To this aim, the Pathology and Genetics Working Party of the European Organisation for Treatment of Trophoblastic Diseases has developed guidelines that describe the pathological criteria and ancillary techniques that can be used in the differential diagnosis of hydatidiform moles. These guidelines are based on the best available evidence in the literature, professional experience and consensus of the experts' group involved in its development.

eng
Keywords
  • Diagnosis
  • Genetics
  • Genotyping
  • Guidelines
  • Hydatidiform moles
  • Pathology
Citation (ISO format)
BARTOSCH, Carla et al. Practical guidelines of the eottd for pathological and genetic diagnosis of hydatidiform moles. In: Virchows Archiv, 2023, vol. 484, n° 3, p. 401–422. doi: 10.1007/s00428-023-03658-8
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ISSN of the journal0945-6317
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