Scientific article

English

Hepatitis B Virus (HBV) Replication During Tenofovir Therapy Is Frequent in Human Immunodeficiency Virus/HBV Coinfection

ContributorsHofmann, Eveline

; Surial, Bernard; Boillat-Blanco, Noémie; Günthard, Huldrych F; Stöckle, Marcel; Bernasconi, Enos; Schmid, Patrick; Calmy, Alexandra

; Suter-Riniker, Franziska; Rauch, Andri; Wandeler, Gilles; Béguelin, Charles; Swiss HIV Cohort Study

CollaboratorsKaiser, Laurent; Keiser, Olivia

; Martinez De Tejada Weber, Begona; Yerly Ferrillo, Sabine

Published inClinical infectious diseases, vol. 76, no. 4, p. 730-733

Publication date2023-02-15

First online date2022-10-15

Abstract

In the Swiss HIV Cohort Study, 61 of 222 (27%) HIV-suppressed persons with chronic hepatitis B virus (HBV) infection had HBV replication after 2 years on tenofovir, of whom 77% were suppressed thereafter. Self-reported adherence to therapy and HBV viral load at tenofovir initiation were predictors of persistent replication.

Keywords

Coinfection
Hepatitis B virus
Human immunodeficiency virus
Tenofovir
Viral replication
Cohort Studies
DNA, Viral
HIV
HIV Infections
Hepatitis B virus / genetics
Hepatitis B
Hepatitis B, Chronic
Humans
Viral Load

Affiliation entities

Faculté de médecine / Section de médecine clinique / Département de médecine

Research groups

VIH/SIDA (930)

Funding

Citation (ISO format)

HOFMANN, Eveline et al. Hepatitis B Virus (HBV) Replication During Tenofovir Therapy Is Frequent in Human Immunodeficiency Virus/HBV Coinfection. In: Clinical infectious diseases, 2023, vol. 76, n° 4, p. 730–733. doi: 10.1093/cid/ciac823

Article (Published version)

Supplemental data

Identifiers

PID : unige:173135
DOI : 10.1093/cid/ciac823
PMID : 36242550

Additional URL for this publicationhttps://academic.oup.com/cid/article/76/4/730/6761485

Journal ISSN1058-4838

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Creation30/01/2023 16:07:55

First validation17/11/2023 18:30:14

Update17/11/2023 18:30:14

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