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Scientific article
Open access
English

Implantation and reimplantation of intracranial EEG electrodes in patients considering epilepsy surgery

Published inEpilepsia open
Publication date2023-11-01
First online date2023-10-23
Abstract

In patients with drug-resistant epilepsy who are considering surgery, intracranial EEG (iEEG) helps delineate the putative epileptogenic zone. In a minority of patients, iEEG fails to identify seizure onsets. In such cases, it might be worthwhile to reimplant more iEEG electrodes. The consequences of such a strategy for the patient are unknown. We matched 12 patients in whom the initially implanted iEEG electrodes did not delineate the seizure onset zone precisely enough to offer resective surgery, and in whom additional iEEG electrodes were implanted during the same inpatient stay, to controls who did not undergo reimplantation. Seven cases and eight controls proceeded to resective surgery. No intracranial infection occurred. One control suffered an intracranial hemorrhage. Three cases and two controls suffered from a post-operative neurological or neuropsychological deficit. We found no difference in post-operative seizure control between cases and controls. Compared to an ILAE score of 5 (ie, stable seizure frequency in the absence of resective surgery), cases showed significant improvement. Reimplantation of iEEG electrodes can offer the possibility of resective epilepsy surgery to patients in whom the initial iEEG investigation was inconclusive, without compromising on the risk of complications or seizure control.

eng
Keywords
  • Complications
  • Outcome
  • Seizure onset zone
Citation (ISO format)
EELBODE, Céline et al. Implantation and reimplantation of intracranial EEG electrodes in patients considering epilepsy surgery. In: Epilepsia open, 2023. doi: 10.1002/epi4.12846
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Identifiers
ISSN of the journal2470-9239
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Technical informations

Creation11/03/2023 9:43:58 AM
First validation11/06/2023 7:58:22 AM
Update time11/06/2023 7:58:22 AM
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