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Book chapter
English

The use of drug-loaded nanoparticles in cancer chemotherapy

Published inMicroencapsulation : Methods and Industrial Applications, Editors Simon Benita, p. 625-671
PublisherNew York : Taylor & Francis
Edition2e édition
Publication date2005
Abstract

Currently, the limiting factor in cancer chemotherapy is the lack of selectivity of anticancer drugs toward neoplastic cells. Generally, rapidly proliferating cells such as those of the bone marrow or the gastrointestinal tract are affected by the cytotoxic action of these drugs. This results in a narrow therapeutic index of most anticancer compounds. Furthermore, the emergence of resistant cell sub lines during the chemotherapeutic treatment IDfY require the use of higher doses of anticancer drugs or the elaboration of dosing protocols combining different anticancer drugs. This, in return, may enhance the toxicity of the treatment.

eng
Keywords
  • Cancer
  • Chemotherapy
  • Nanoparticles
Citation (ISO format)
LEROUX, Jean-Christophe et al. The use of drug-loaded nanoparticles in cancer chemotherapy. In: Microencapsulation : Methods and Industrial Applications. New York : Taylor & Francis, 2005. p. 625–671.
Main files (1)
Book chapter (Published version)
accessLevelRestricted
Identifiers
  • PID : unige:171269
ISBN9781420027990
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