UNIGE document Scientific Article
previous document  unige:1709  next document
add to browser collection

Rapid identification of hospitalized patients at high risk for MRSA carriage

Evans, R Scott
Wallace, Carrie Jane
Lloyd, James F.
Taylor, Caroline W.
Abouzelof, Rouett H.
Sumner, Sharon
Johnson, Kyle V.
Wuthrich, Amyanne
show hidden authors show all authors [1 - 10]
Published in Journal of the American Medical Informatics Association. 2008, vol. 15, no. 4, p. 506-12
Abstract Patients who are asymptomatic carriers of methicillin-resistant Staphylococcus aureus (MRSA) are major reservoirs for transmission of MRSA to other patients. Medical personnel are usually not aware when these high-risk patients are hospitalized. We developed and tested an enterprise-wide electronic surveillance system to identify patients at high risk for MRSA carriage at hospital admission and during hospitalization. During a two-month study, nasal swabs from 153 high-risk patients were tested for MRSA carriage using polymerase chain reaction (PCR) of which 31 (20.3%) were positive compared to 12 of 293 (4.1%, p < 0.001) low-risk patients. The mean interval from admission to availability of PCR test results was 19.2 hours. Computer alerts for patients at high-risk of MRSA carriage were found to be reliable, timely and offer the potential to replace testing all patients. Previous MRSA colonization was the best predictor but other risk factors were needed to increase the sensitivity of the algorithm.
Keywords AlgorithmsCarrier State/diagnosisCross Infection/prevention & controlDecision Support Systems, ClinicalDisease ReservoirsDisease Transmission, Infectious/prevention & controlHospitalizationHumansInfection Control/methodsMedical Records Systems, ComputerizedMethicillin ResistanceNose/microbiologyPopulation Surveillance/methodsReminder SystemsRiskStaphylococcal Infections/diagnosisStaphylococcus aureus/isolation & purificationTime Factors
PMID: 18436898
Full text
Research groups CDC Prevention Epicenter Program
Epidémiologie et contrôle de la résistance aux antibiotiques (866)
(ISO format)
EVANS, R Scott et al. Rapid identification of hospitalized patients at high risk for MRSA carriage. In: Journal of the American Medical Informatics Association, 2008, vol. 15, n° 4, p. 506-12. doi: 10.1197/jamia.M2721 https://archive-ouverte.unige.ch/unige:1709

450 hits

1 download


Deposited on : 2009-05-25

Export document
Format :
Citation style :