The Effect of Solvent Variation on Nucleophilic Substitution Rates of Methyl Tosylate

Muller, Paul; Siegfried, Bernard

doi:10.1002/hlca.19720550714

Scientific article

English

The Effect of Solvent Variation on Nucleophilic Substitution Rates of Methyl Tosylate

ContributorsMuller, Paul; Siegfried, Bernard

Published inHelvetica chimica acta, vol. 55, no. 7, p. 2400-2406

Publication date1972-11-01

First online date2004-10-25

Abstract

Rates of the reactions between bromide ion and methyl tosylate have been determined in 12 solvents and extrapolated to infinite dilution. The data are correlated with Parker's solvent activity coefficients by means of an empirical equation of the type: logk^s – logk⁰ = A log⁰γ + B with the constants A = 0.788 and B = 0,108 and a correlation coefficient of 0.983.

Affiliation

Faculté des sciences / Section de chimie et biochimie / Département de chimie organique

Citation (ISO format)

MULLER, Paul, SIEGFRIED, Bernard. The Effect of Solvent Variation on Nucleophilic Substitution Rates of Methyl Tosylate. In: Helvetica chimica acta, 1972, vol. 55, n° 7, p. 2400–2406. doi: 10.1002/hlca.19720550714

Article (Published version)

Identifiers

PID : unige:169585
DOI : 10.1002/hlca.19720550714

Commercial URLhttps://onlinelibrary.wiley.com/doi/10.1002/hlca.19720550714

ISSN of the journal0018-019X

20views

0downloads

Creation06/16/2023 8:25:00 AM

First validation06/19/2023 8:49:43 AM

Update time06/19/2023 8:49:43 AM

Status update06/19/2023 8:49:43 AM

Last indexation02/01/2024 10:15:31 AM

Archive ouverte UNIGE

The Effect of Solvent Variation on Nucleophilic Substitution Rates of Methyl Tosylate

Technical informations