The Effect of Solvent Variation on Nucleophilic Substitution Rates of Methyl Tosylate

Muller, Paul; Siegfried, Bernard

doi:10.1002/hlca.19720550714

Scientific article

English

The Effect of Solvent Variation on Nucleophilic Substitution Rates of Methyl Tosylate

ContributorsMuller, Paul; Siegfried, Bernard

Published inHelvetica chimica acta, vol. 55, no. 7, p. 2400-2406

Publication date1972-11-01

First online date2004-10-25

Abstract

Rates of the reactions between bromide ion and methyl tosylate have been determined in 12 solvents and extrapolated to infinite dilution. The data are correlated with Parker's solvent activity coefficients by means of an empirical equation of the type: logk^s – logk⁰ = A log⁰γ + B with the constants A = 0.788 and B = 0,108 and a correlation coefficient of 0.983.

Affiliation entities

Faculté des sciences / Section de chimie et biochimie / Département de chimie organique

Citation (ISO format)

MULLER, Paul, SIEGFRIED, Bernard. The Effect of Solvent Variation on Nucleophilic Substitution Rates of Methyl Tosylate. In: Helvetica chimica acta, 1972, vol. 55, n° 7, p. 2400–2406. doi: 10.1002/hlca.19720550714

Article (Published version)

Identifiers

PID : unige:169585
DOI : 10.1002/hlca.19720550714

Additional URL for this publicationhttps://onlinelibrary.wiley.com/doi/10.1002/hlca.19720550714

Journal ISSN0018-019X

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The Effect of Solvent Variation on Nucleophilic Substitution Rates of Methyl Tosylate

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