Scientific article
English

A Convergent Synthesis of (±)-α- and β-Himachalenes

Published inHelvetica chimica acta, vol. 64, no. 8, p. 2592-2597
Publication date1981-12-16
Abstract

(±)-α and β-Himachalene, 5 and 6, have been synthesized in a convergent manner from 3,3-dimethylacrolein (9), the ester enolate 10 and the silyloxypentadienyllithium 7. The key steps are the regioselective γ-addition of the dienal 13 to 7 and the intramolecular Diels-Alder addition 15 → 16. Hydrogenolysis of the diethylphosphate group and functionalization at C (5) completed the synthesis of 5 and 6.

Citation (ISO format)
VON OPPOLZER, Wolfgang, SNOWDEN, Roger. A Convergent Synthesis of (±)-α- and β-Himachalenes. In: Helvetica chimica acta, 1981, vol. 64, n° 8, p. 2592–2597. doi: 10.1002/hlca.19810640815
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Journal ISSN0018-019X
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