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Quantification of Myocardial Perfusion with MRI and Exogenous Contrast Agents

ContributorsVallée, Jean-Paulorcid; Sostman, H.D.; MacFall, J.R.; Coleman, R.E.
Published inCardiology, vol. 88, no. 1, p. 90-105
Publication date1997-01
Abstract

This review discusses the applications of MRI to quantification of the myocardial perfusion. The first step of the measurement is to obtain a concentration-time curve from a signal intensity-time (SI) curve. Factors which influence the correlation between SI and the concentration are discussed for relaxivity and susceptibility agents. The second stage of measurement is to extract parameters of myocardial perfusion from the concentration-time curve. Two methods are considered, one for an intravascular agent and the other for an extravascular agent. Key points are illustrated with experimental data.

Keywords
  • Animals
  • Blood Flow Velocity
  • Contrast Media / administration & dosage
  • Coronary Disease / diagnosis
  • Coronary Disease / physiopathology
  • Humans
  • Infusions, Intra-Arterial
  • Magnetic Resonance Angiography / methods
Affiliation entities Not a UNIGE publication
Research groups
Citation (ISO format)
VALLÉE, Jean-Paul et al. Quantification of Myocardial Perfusion with MRI and Exogenous Contrast Agents. In: Cardiology, 1997, vol. 88, n° 1, p. 90–105. doi: 10.1159/000177315
Main files (1)
Article (Published version)
accessLevelRestricted
Identifiers
Additional URL for this publicationhttps://www.karger.com/Article/Abstract/177315
Journal ISSN0008-6312
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