Severe autoimmune hemolytic anemia in a liver transplanted child

Schaeppi, Michela; Ozsahin, Ayse Hulya; Peyrard, Thierry; Gumy Pause, Fabienne; Posfay Barbe, Klara; Chardot, Christophe; Belli, Dominique Charles; Siegenthaler, Michèle A.

doi:10.1111/j.1399-3046.2008.00934.x

Scientific article

English

Severe autoimmune hemolytic anemia in a liver transplanted child

Contributors

Schaeppi, Michela; Ozsahin, Ayse Hulya; Peyrard, Thierry; Gumy Pause, Fabienne

; Posfay Barbe, Klara; Chardot, Christophe; Belli, Dominique Charles; Siegenthaler, Michèle A.

Published in

Pediatric transplantation, vol. 12, no. 7, p. 809-812

Publication date

2008

Abstract

AIHA can complicate solid organ and bone marrow transplantation early after transplant. We describe the first case report of a 16-month-old boy with mixed type warm-acting IgM and warm IgG autoantibodies AIHA, occurring eight months after liver transplantation. This case describes the complexity of this very rare form of AIHA. It also illustrates the efficacy of rituximab in this indication, as well as the transfusion support with extremely rare blood, along with the importance of international collaboration to provide it. In this report, the etiologies of HA occurring in post-transplant pediatric patients are reviewed and the different treatment strategies are discussed.

Keywords

Anemia, Hemolytic, Autoimmune/complications/etiology
Antibodies, Monoclonal/administration & dosage/chemistry
Autoantibodies/chemistry
Blood Transfusion
Child
Humans
Immunoglobulin G/chemistry
Immunoglobulin M/chemistry
Immunologic Factors/administration & dosage
Infant
Liver Diseases/complications
Liver Transplantation/adverse effects/methods
Male

UNIGE affiliation entities

UNIGE research groups

Citation (ISO format)

SCHAEPPI, Michela et al. Severe autoimmune hemolytic anemia in a liver transplanted child. In: Pediatric transplantation, 2008, vol. 12, n° 7, p. 809–812. doi: 10.1111/j.1399-3046.2008.00934.x

Article (Accepted version)

Identifiers

PID : unige:1678
DOI : 10.1111/j.1399-3046.2008.00934.x
PMID : 18433411

Journal ISSN

1397-3142

677views

0downloads

Creation

20/05/2009 16:02:00

First validation

20/05/2009 16:02:00

Update

14/03/2023 15:05:21

Status update

14/03/2023 15:05:21

Last indexation

29/10/2024 11:34:57

Severe autoimmune hemolytic anemia in a liver transplanted child

Contributors

Published in

Publication date

Abstract

Keywords

UNIGE affiliation entities

UNIGE research groups

Citation (ISO format)

Main files (1)

Identifiers

Journal ISSN

Technical informations

Creation

First validation

Update

Status update

Last indexation