Imaging Protein Dynamics in Liquid Water

De Pace, Cesare; Acosta-Gutierrez, Silvia; Ing, Gabriel; Marchello, Gabriele; Pilotto, Simona; Werner, Finn; Wilkinson, Neil; Leite, Diana; Gervasio, Francesco Luigi; Ruiz-Pérez, Lorena; Battaglia, Giuseppe

doi:10.1017/S1431927621013076

Scientific article

English

Imaging Protein Dynamics in Liquid Water

ContributorsDe Pace, Cesare; Acosta-Gutierrez, Silvia; Ing, Gabriel; Marchello, Gabriele; Pilotto, Simona; Werner, Finn; Wilkinson, Neil; Leite, Diana; Gervasio, Francesco Luigi

; Ruiz-Pérez, Lorena; Battaglia, Giuseppe

Published inMicroscopy and microanalysis, vol. 27, no. S2, p. 15-16

Publication date2021-11

First online date2021-11-01

Abstract

We propose the combination of all-atom simulations with LP EM to complement structural studies with dynamic investigations. In this work, we exploited LPEM to image the dynamics of proteins undergoing.Brownian motion, using their natural rotation to access the particle structural landscape for reconstructing its architecture in 3D using tomographic techniques.

Affiliation entities

Faculté des sciences / Section des sciences pharmaceutiques

Research groups

Modélisation biomoléculaire et pharmaceutique

Funding

UK Research and Innovation - Video Liquid Transmission Electron Microscopy [EP/N010906/1]

Citation (ISO format)

DE PACE, Cesare et al. Imaging Protein Dynamics in Liquid Water. In: Microscopy and microanalysis, 2021, vol. 27, n° S2, p. 15–16. doi: 10.1017/S1431927621013076

Article (Published version)

Identifiers

PID : unige:167767
DOI : 10.1017/S1431927621013076

Additional URL for this publicationhttps://academic.oup.com/mam/article/27/S2/15/6712451

Journal ISSN1431-9276

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Imaging Protein Dynamics in Liquid Water

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