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The synthesis of an amine-bearing polymerizable phospholipid

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Published in Tetrahedron Letters. 2011, vol. 52, no. 32, p. 4215-4217
Abstract Exchange of the natural glycerol phospholipid backbone with an artificial 1,3-diaminopropanol backbone led to the first synthetic 1,3-diaminophospholipid. The amines in the polar head group region were reacted to acrylamides giving a UV polymerizable phospholipid. Preliminary experiments demonstrate that formulated vesicles can be polymerized into large aggregates of vesicles.
Keywords Artificial phospholipidsPhospholipid synthesisAmine-bearing phospholipidsPolymerizable phospholipidsPolymeric vesicles
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ZAFFALON, Pierre Léonard et al. The synthesis of an amine-bearing polymerizable phospholipid. In: Tetrahedron Letters, 2011, vol. 52, n° 32, p. 4215-4217. https://archive-ouverte.unige.ch/unige:16742

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Deposited on : 2011-08-05

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