The G-protein-gated K+ channel, IKACh, is required for regulation of pacemaker activity and recovery of resting heart rate after sympathetic stimulation
Published inThe Journal of general physiology, vol. 142, no. 2, p. 113-126
Publication date2013-08
First online date2013-07-15
Abstract
Keywords
- Acetylcholine / pharmacology
- Action Potentials
- Animals
- Electrocardiography
- G Protein-Coupled Inwardly-Rectifying Potassium Channels / genetics
- G Protein-Coupled Inwardly-Rectifying Potassium Channels / metabolism
- Heart Rate
- Mice
- Mice, Inbred C57BL
- Mice, Knockout
- Myocardial Reperfusion
- Myocytes, Cardiac / drug effects
- Myocytes, Cardiac / metabolism
- Myocytes, Cardiac / physiology
- Physical Exertion
- Protein Subunits / genetics
- Protein Subunits / metabolism
- Sinoatrial Node / cytology
- Sinoatrial Node / drug effects
- Sinoatrial Node / innervation
- Sinoatrial Node / physiology
- Stress, Physiological
- Sympathetic Nervous System / physiology
Affiliation entities Not a UNIGE publication
Citation (ISO format)
MESIRCA, Pietro et al. The G-protein-gated K+ channel, IKACh, is required for regulation of pacemaker activity and recovery of resting heart rate after sympathetic stimulation. In: The Journal of general physiology, 2013, vol. 142, n° 2, p. 113–126. doi: 10.1085/jgp.201310996
Main files (1)
Article (Published version)
Secondary files (10)
Identifiers
- PID : unige:167337
- DOI : 10.1085/jgp.201310996
- PMID : 23858001
- PMCID : PMC3727310
ISSN of the journal0022-1295