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Scientific article
English

Asymmetric induction at C(β) and C(α) of N-enoyl sultams by 1,4-hydride addition/enolate trapping

Published inTetrahedron letters, vol. 27, no. 39, p. 4717-4720
Publication date1986
Abstract

Conjugate addition of L-Selectride to α, β-enoyl sultams 1 and 4 followed by electrophilic trapping of the resulting enolates gave in one operation saturated imides with high β- and/or α- stereodifferentiation. Starting from enoylsultams, 1,4-reduction with L-Selectride followed by protonation or methylation gave α- and/or β-substituted imides with high asymmetric induction at both centers.

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Citation (ISO format)
VON OPPOLZER, Wolfgang, POLI, Giovanni. Asymmetric induction at C(<i>β</i>) and C(<i>α</i>) of N-enoyl sultams by 1,4-hydride addition/enolate trapping. In: Tetrahedron letters, 1986, vol. 27, n° 39, p. 4717–4720. doi: 10.1016/S0040-4039(00)85046-7
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ISSN of the journal0040-4039
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