Efficient asymmetric hydrogenations of camphor-sultam-imide-conjugated alkenes

Von Oppolzer, Wolfgang; Mills, Robert John; Reglier, Marius Louis Jean

doi:10.1016/S0040-4039(00)83972-6

Scientific article

English

Efficient asymmetric hydrogenations of camphor-sultam-imide-conjugated alkenes

ContributorsVon Oppolzer, Wolfgang; Mills, Robert John; Reglier, Marius Louis Jean

Published inTetrahedron letters, vol. 27, no. 2, p. 183-186

Publication date1986

Abstract

The trisubstituted olefinic bond of sultam-imides 2 was hydrogenated in the presence of Pd/C with >90% diastereoface discrimination to give after saponification recovered auxiliary 7 and the β-substituted carboxylic acids 5 or 6 in high e.e.

Affiliation entities

Faculté des sciences / Section de chimie et biochimie / Département de chimie organique

Citation (ISO format)

VON OPPOLZER, Wolfgang, MILLS, Robert John, REGLIER, Marius Louis Jean. Efficient asymmetric hydrogenations of camphor-sultam-imide-conjugated alkenes. In: Tetrahedron letters, 1986, vol. 27, n° 2, p. 183–186. doi: 10.1016/S0040-4039(00)83972-6

Article (Published version)

Identifiers

PID : unige:167137
DOI : 10.1016/S0040-4039(00)83972-6

Commercial URLhttps://linkinghub.elsevier.com/retrieve/pii/S0040403900839726

Journal ISSN0040-4039

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Efficient asymmetric hydrogenations of camphor-sultam-imide-conjugated alkenes

The trisubstituted olefinic bond of sultam-imides 2 was hydrogenated in the presence of Pd/C with >90% diastereoface discrimination to give after saponification recovered auxiliary 7 and the β-substituted carboxylic acids 5 or 6 in high e.e.

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