Asymmetric syntheses of α-amino acids from α-halogenated 10-sulfonamido-isobornyl esters

Von Oppolzer, Wolfgang; Pedrosa, Rafaël; Moretti, Robert

doi:10.1016/S0040-4039(00)84112-X

Scientific article

English

Asymmetric syntheses of α-amino acids from α-halogenated 10-sulfonamido-isobornyl esters

ContributorsVon Oppolzer, Wolfgang; Pedrosa, Rafaël; Moretti, Robert

Published inTetrahedron letters, vol. 27, no. 7, p. 831-834

Publication date1986

Abstract

Treatment of chiral α-haloesters 2 with NaN₃ gave azidoesters 3 which on successive transesterification and hydrogenolysis furnished α-amino acids 5 and 9 in high e.e.

Affiliation entities

Faculté des sciences / Section de chimie et biochimie / Département de chimie organique

Citation (ISO format)

VON OPPOLZER, Wolfgang, PEDROSA, Rafaël, MORETTI, Robert. Asymmetric syntheses of α-amino acids from α-halogenated 10-sulfonamido-isobornyl esters. In: Tetrahedron letters, 1986, vol. 27, n° 7, p. 831–834. doi: 10.1016/S0040-4039(00)84112-X

Article (Published version)

Identifiers

PID : unige:167135
DOI : 10.1016/S0040-4039(00)84112-X

Commercial URLhttps://linkinghub.elsevier.com/retrieve/pii/S004040390084112X

Journal ISSN0040-4039

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Asymmetric syntheses of α-amino acids from α-halogenated 10-sulfonamido-isobornyl esters

Treatment of chiral α-haloesters 2 with NaN3 gave azidoesters 3 which on successive transesterification and hydrogenolysis furnished α-amino acids 5 and 9 in high e.e.

Technical informations

Treatment of chiral α-haloesters 2 with NaN₃ gave azidoesters 3 which on successive transesterification and hydrogenolysis furnished α-amino acids 5 and 9 in high e.e.