Objective: The aim of this study was to investigate a new digital 3-D infra-red video system to determine its accuracy, precision and validity in measuring facial distances. Methods: Bench experiments were performed by measuring the vertical and diagonal distances of chessboard squares of known length to determine the system's accuracy and precision. To test the system's validity sixteen healthy volunteers, participated in this study. Vertical and horizontal distances of the face were measured electronically at rest, at “posed” and “aggressive smile”. All measurements were repeated after 8 weeks. Direct measurements of the intercanthal distance were obtained twice with calipers. Results: A minor systematic error was detected in the bench experiments with a highest absolute error of 0.227 ±0.39 mm. The analysis using this video system revealed a good reproducibility of all measured distances when the mean of two frames was used to compare distances. Digital measurements of the intercanthal distance showed a high agreement with the clinically obtained values. Conclusion: The examined digital video system is able to measure geometrical distances in a 3D environment with high precision. Facial distances can be measured with good accuracy and precision, allowing its application in research and clinical practice.