Protein Release from Poly(ortho ester) Extruded Rods

Rothen-Weinhold, Alexandra Laurence; Barr, John; Ng, Steven Y.; Shen, Hui-Rong; Gurny, Robert; Heller, Jorge

doi:10.1002/1521-3900(200107)172:1<67::AID-MASY67>3.0.CO;2-5

Scientific article

English

Protein Release from Poly(ortho ester) Extruded Rods

ContributorsRothen-Weinhold, Alexandra Laurence; Barr, John; Ng, Steven Y.; Shen, Hui-Rong; Gurny, Robert; Heller, Jorge

Published inMacromolecular symposia, vol. 172, p. 67-72

Publication date2001

Abstract

Poly(ortho ester) rods containing 15 wt% FITC-BSA were prepared by extruding an intimate mixture of finely powdered polymer and protein at a temperature where protein activity is retained. After an induction period, linear in vitro release kinetics were obtained with concomitant polymer weight loss.

Affiliation entities

Faculté des sciences / Section des sciences pharmaceutiques

Citation (ISO format)

ROTHEN-WEINHOLD, Alexandra Laurence et al. Protein Release from Poly(ortho ester) Extruded Rods. In: Macromolecular symposia, 2001, vol. 172, p. 67–72. doi: 10.1002/1521-3900(200107)172:1<67::AID-MASY67>3.0.CO;2-5

Article (Published version)

Identifiers

PID : unige:166294
DOI : 10.1002/1521-3900(200107)172:1<67::AID-MASY67>3.0.CO;2-5

Journal ISSN1022-1360

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Protein Release from Poly(ortho ester) Extruded Rods

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