Scientific article
Open access

Degenerated Serous Cystic Tumor of the Pancreas: Case Report and Literature Review of an Aggressive Presentation of a Benign Tumor

Published inThe American journal of case reports, vol. 23, e936165
Publication date2022-08-15
First online date2022-07-05

BACKGROUND: Serous cystic tumors of the pancreas are known to present a benign nature and course, not requiring surgery in the absence of symptoms. In rare cases, these benign tumors may present aggressive characteristics such as local infiltration and lymph node and distant metastases. In such cases, a surgical approach may be necessary.

CASE REPORT: We present the case of a 79-year-old woman with an asymptomatic cytologically suggested caudal serous cystic tumor infiltrating the spleen and the splenic vein. This tumor was discovered in a computed tomography scan in the setting of evaluating distant spreading of a primary malignant neoplasm of the rectum. Suspicious malignant signs on imaging dictated a surgical approach and a distal splenopancreatectomy was carried out in the same operative time as the transanal resection of the rectal lesion. The nature of the pancreatic neoplasm was confirmed by histology, but 2 lymph nodes out of 4 retrieved were positive. The postoperative course was uneventful. No adjuvant treatment was proposed. Imaging control 6 months after surgery was not indicative of relapse.

CONCLUSIONS: Serous cystic adenomas of the pancreas, although generally considered benign neoplasms, may present with characteristics of malignancy. Moreover, they may prove difficult to differentiate from other malignant neoplasms by non-surgical modalities. Although current guidelines and data from the literature provide controversial information regarding management of these clinical entities, in the presence of suspicious radiological aspects, surgical resection could be considered.

  • Abdomen
  • Aged
  • Female
  • Humans
  • Neoplasm Recurrence, Local / pathology
  • Pancreas
  • Pancreatic Neoplasms / diagnostic imaging
  • Pancreatic Neoplasms / surgery
  • Tomography, X-Ray Computed
Citation (ISO format)
PAPAZARKADAS, Xenofon et al. Degenerated Serous Cystic Tumor of the Pancreas: Case Report and Literature Review of an Aggressive Presentation of a Benign Tumor. In: The American journal of case reports, 2022, vol. 23, p. e936165. doi: 10.12659/AJCR.936165
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Article (Published version)
ISSN of the journal1941-5923

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Creation08/24/2022 2:07:00 PM
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Update time03/16/2023 10:25:30 AM
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