Scientific article

Ni-Catalyzed Enantioselective Hydrofunctionalizations of 1,3-Dienes

Published inACS Catalysis, vol. 12, no. 24, p. 15638-15647
Publication date2022-12-16
First online date2022-12-06

Ni-catalyzed enantioselective hydrofunctionalizations of conjugated dienes are particularly demanding reactions to devise because they require not only addressing the inherent challenges associated with the development of an enantioselective transformation but also overcoming all other aspects of selective catalysis (chemoselectivity, regioselectivity, diastereoselectivity, etc.). However, the value-added nature of the chiral allylic and homoallylic derivatives obtained by these methods, the lack of efficient alternatives, and the use of an earth-abundant first-row transition metal have led to renewed interest over the past decade. In this Perspective, we give an overview of the developments in this field, from the original findings (often dating back to the last century) to the most recent contributions. Emphasis is placed on the nature of the hydrofunctionalization agent (C(sp), C(sp2), C(sp3), N, P, or O).

  • Amines
  • Ligands
  • Organic reactions
  • Selectivity
  • Stereoselectivity
Research group
Citation (ISO format)
FLAGET, Arthur, ZHANG, Cheng, MAZET, Clement. Ni-Catalyzed Enantioselective Hydrofunctionalizations of 1,3-Dienes. In: ACS Catalysis, 2022, vol. 12, n° 24, p. 15638–15647. doi: 10.1021/acscatal.2c05251
Main files (1)
Article (Published version)
ISSN of the journal2155-5435

Technical informations

Creation01/03/2023 9:18:00 AM
First validation01/03/2023 9:18:00 AM
Update time03/16/2023 10:19:50 AM
Status update03/16/2023 10:19:49 AM
Last indexation02/01/2024 9:22:51 AM
All rights reserved by Archive ouverte UNIGE and the University of GenevaunigeBlack