Book chapter

Chapter 18. Genetic Obesity Syndromes

Published inBrook's Clinical Pediatric Endocrinology, Editors Mehul T. Dattani, Charles G. D. Brook, p. 729-736
PublisherHoboken, NJ : Wiley-Blackwell
Edition7th ed.
Publication date2020
First online date2019-08-30

The rising prevalence of childhood obesity is driven by factors that promote an increase in energy intake and factors that contribute to a decrease in energy expenditure such as sedentary lifestyles and reduced physical activity at school and in leisure time. As the number of children presenting for clinical assessment is increasing, pediatricians need a systematic approach to the assessment of severe childhood-onset obesity and to consider genetic causes. For the purposes of clinical assessment, it remains useful to categorize the genetic obesity syndromes as those with dysmorphism and/or developmental delay and those without these features, but the spectrum of clinical features can be quite variable. The diagnosis of a genetic obesity syndrome can provide information that has diagnostic value for the family to whom genetic counselling can be provided. A genetic diagnosis can inform management and can inform clinical decision-making regarding the use of bariatric surgery.

Affiliation Not a UNIGE publication
Research group
Citation (ISO format)
COLLET, Tinh-Hai, FAROOQI, I. Sadaf. Chapter 18. Genetic Obesity Syndromes. In: Brook’s Clinical Pediatric Endocrinology. Hoboken, NJ : Wiley-Blackwell, 2020. p. 729–736. doi: 10.1002/9781119152712.ch18
Main files (2)
Book chapter (Accepted version)
Book chapter (Published version)

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