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Title

Restless legs syndrome: an early manifestation of Huntington's disease?

Authors
Savva, E.
Schnorf, H.
Published in Acta Neurologica Scandinavica. 2009, vol. 119, no. 4, p. 274-276
Abstract BACKGROUND: Far from being uniform, Huntington's disease (HD)'s phenotype encompasses a large variety of motor and non-motor symptoms which occur in various combinations in individual patients. AIM: To describe an unusual association between restless legs syndrome (RLS) and HD. METHODS AND RESULTS: We report a patient with an atypical presentation of genetically demonstrated HD, who developed typical RLS a few years prior to and during the course of HD. Common causes of RLS were excluded and the polysomnography confirmed frequent and severe periodic limb movements during sleep and while awake. CONCLUSIONS: We propose RLS as an uncommon but early feature of HD in some patients, and suggest adding HD to the already long list of RLS secondary to neurodegenerative conditions.
Keywords HumansHuntington Disease/complications/diagnosisMaleMiddle AgedPolysomnographyRestless Legs Syndrome/complications/drug therapy
Identifiers
PMID: 18759800
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Research group Groupe Pierre Burkhard (neurologie) (154)
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(ISO format)
SAVVA, E., SCHNORF, H., BURKHARD, Pierre. Restless legs syndrome: an early manifestation of Huntington's disease?. In: Acta Neurologica Scandinavica, 2009, vol. 119, n° 4, p. 274-276. https://archive-ouverte.unige.ch/unige:1648

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Deposited on : 2009-05-18

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