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Scientific article
English

Restless legs syndrome: an early manifestation of Huntington's disease?

Contributors

Savva, E.; Schnorf, H.; Burkhard, Pierre

Published in

Acta neurologica Scandinavica, vol. 119, no. 4, p. 274-276

Publication date

2009

Abstract

BACKGROUND: Far from being uniform, Huntington's disease (HD)'s phenotype encompasses a large variety of motor and non-motor symptoms which occur in various combinations in individual patients. AIM: To describe an unusual association between restless legs syndrome (RLS) and HD. METHODS AND RESULTS: We report a patient with an atypical presentation of genetically demonstrated HD, who developed typical RLS a few years prior to and during the course of HD. Common causes of RLS were excluded and the polysomnography confirmed frequent and severe periodic limb movements during sleep and while awake. CONCLUSIONS: We propose RLS as an uncommon but early feature of HD in some patients, and suggest adding HD to the already long list of RLS secondary to neurodegenerative conditions.

Keywords

  • Humans
  • Huntington Disease/complications/diagnosis
  • Male
  • Middle Aged
  • Polysomnography
  • Restless Legs Syndrome/complications/drug therapy

UNIGE affiliation entities

UNIGE research groups

Citation (ISO format)

SAVVA, E., SCHNORF, H., BURKHARD, Pierre. Restless legs syndrome: an early manifestation of Huntington’s disease? In: Acta neurologica Scandinavica, 2009, vol. 119, n° 4, p. 274–276. doi: 10.1111/j.1600-0404.2008.01091.x

Main files (1)

Article (Accepted version)

Identifiers

Journal ISSN

0001-6314
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Technical informations

Creation

30/03/2009 10:22:00

First validation

30/03/2009 10:22:00

Update

14/03/2023 15:05:15

Status update

14/03/2023 15:05:15

Last indexation

29/10/2024 11:34:10
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