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Scientific article
Open access
English

Time to death and risk factors associated with mortality among COVID-19 cases in countries within the WHO African region in the early stages of the COVID-19 pandemic

Published inEpidemiology and infection, vol. 150, p. 1-29
First online date2022-02-18
Abstract

This study describes risk factors associated with mortality among COVID-19 cases reported in the WHO African region between 21 March and 31 October 2020. Average hazard ratios of death were calculated using weighted Cox regression as well as median time to death for key risk factors. We included 46 870 confirmed cases reported by eight Member States in the region. The overall incidence was 20.06 per 100 000, with a total of 803 deaths and a total observation time of 3 959 874 person-days. Male sex (aHR 1.54 (95% CI 1.31–1.81); P < 0.001), older age (aHR 1.08 (95% CI 1.07–1.08); P < 0.001), persons who lived in a capital city (aHR 1.42 (95% CI 1.22–1.65); P < 0.001) and those with one or more comorbidity (aHR 36.37 (95% CI 20.26–65.27); P < 0.001) had a higher hazard of death. Being a healthcare worker reduced the average hazard of death by 40% (aHR 0.59 (95% CI 0.37–0.93); P = 0.024). Time to death was significantly less for persons ≥60 years (P = 0.038) and persons residing in capital cities (P < 0.001). The African region has COVID-19-related mortality similar to that of other regions, and is likely underestimated. Similar risk factors contribute to COVID-19-associated mortality as identified in other regions.

eng
Keywords
  • Comorbidities
  • COVID-19
  • Mortality
  • Risk factors
  • SARS-CoV-2
Funding
  • World Health Organization - [001]
Citation (ISO format)
IMPOUMA, Benido et al. Time to death and risk factors associated with mortality among COVID-19 cases in countries within the WHO African region in the early stages of the COVID-19 pandemic. In: Epidemiology and infection, 2022, vol. 150, p. 1–29. doi: 10.1017/S095026882100251X
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Identifiers
ISSN of the journal0950-2688
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Creation07/28/2022 12:53:00 PM
First validation07/28/2022 12:53:00 PM
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