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Scientific article
English

A novel range telescope concept for proton CT

Published inPhysics in medicine and biology, vol. 67, no. 3, 035013
Publication date2022-02-03
First online date2022-02-03
Abstract

Proton beam therapy can potentially offer improved treatment for cancers of the head and neck and in paediatric patients. There has been a sharp uptake of proton beam therapy in recent years as improved delivery techniques and patient benefits are observed. However, treatments are currently planned using conventional x-ray CT images due to the absence of devices able to perform high quality proton computed tomography (pCT) under realistic clinical conditions. A new plastic-scintillator-based range telescope concept, named ASTRA, is proposed here to measure the proton’s energy loss in a pCT system. Simulations conducted using GEANT4 yield an expected energy resolution of 0.7%. If calorimetric information is used the energy resolution could be further improved to about 0.5%. In addition, the ability of ASTRA to track multiple protons simultaneously is presented. Due to its fast components, ASTRA is expected to reach unprecedented data collection rates, similar to 10 8 protons/s. The performance of ASTRA has also been tested by simulating the imaging of phantoms. The results show excellent image contrast and relative stopping power reconstruction.

eng
Keywords
  • CT scan
  • Monte Carlo simulation
  • Proton CT
  • Proton therapy
  • Range telescope
  • Tracking
Funding
  • UK Research and Innovation - OPTIma: Optimising Proton Therapy through Imaging [EP/R023220/1]
Citation (ISO format)
GRANADO-GONZÁLEZ, M et al. A novel range telescope concept for proton CT. In: Physics in medicine and biology, 2022, vol. 67, n° 3, p. 035013. doi: 10.1088/1361-6560/ac4b39
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ISSN of the journal0031-9155
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Creation10/06/2022 10:16:00 AM
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