A signaling factor linked to Toxoplasma gondii guanylate cyclase complex controls invasion and egress during acute and chronic infection

Ye, Shu; Lunghi, Matteo; Soldati-Favre, Dominique

doi:10.1128/mbio.01965-22

Scientific article

English

A signaling factor linked to Toxoplasma gondii guanylate cyclase complex controls invasion and egress during acute and chronic infection

ContributorsYe, Shu; Lunghi, Matteo; Soldati-Favre, Dominique

Published inMBio, p. e01965-22

Publication date2022-10-06

First online date2022-10-06

Abstract

Toxoplasma gondii is an obligate intracellular parasite of the phylum Apicomplexa. This life-threatening opportunistic pathogen establishes a chronic infection in human and animals that is resistant to immune attacks and chemotherapeutic intervention.

Affiliation entities

Faculté de médecine / Section de médecine fondamentale / Département de microbiologie et médecine moléculaire

Research groups

Biologie d'un parasite intracellulaire obligatoire (773)

Funding

Swiss National Science Foundation - Structure-Function Relationship of the Guanylate Cyclase Signaling Platform in Apicomplexa [CRSII5_198545]

Citation (ISO format)

YE, Shu, LUNGHI, Matteo, SOLDATI-FAVRE, Dominique. A signaling factor linked to Toxoplasma gondii guanylate cyclase complex controls invasion and egress during acute and chronic infection. In: MBio, 2022, p. e01965–22. doi: 10.1128/mbio.01965-22

Article (Published version)

CC BY-4.0

Identifiers

PID : unige:164053
DOI : 10.1128/mbio.01965-22
PMID : 36200777

Commercial URLhttps://journals.asm.org/doi/10.1128/mbio.01965-22

Journal ISSN2150-7511

184views

129downloads

Creation06/10/2022 13:50:00

First validation06/10/2022 13:50:00

Update time16/03/2023 07:55:42

Status update16/03/2023 07:55:41

Last indexation01/11/2024 02:59:58

Archive ouverte UNIGE

A signaling factor linked to Toxoplasma gondii guanylate cyclase complex controls invasion and egress during acute and chronic infection

Toxoplasma gondii is an obligate intracellular parasite of the phylum Apicomplexa. This life-threatening opportunistic pathogen establishes a chronic infection in human and animals that is resistant to immune attacks and chemotherapeutic intervention.

Technical informations