This paper focuses on the visual and material dimensions of the dedications found in the Asclepieion of Pergamon. To assess them, their findspots are mapped on the sanctuary plan; four main assemblages are highlighted, each characterised by a particular type of support. Some of them clearly display investment by the elite, based on the dedication of conspicuous offerings near honorific statues and building endowments. Three case studies show the potential of analysing textual, material and spatial elements in order to better understand the message each dedication carried. The case of the Asclepieion of Pergamon proves that the impression made by dedications on the visitors of the sanctuary was based not only on their text, but on the combination of wording, support and location, as well as on the interplay among different inscriptions. Understanding such dynamics enhances our understanding of the sanctuary as a whole.