Cell division: the science friction of chromosome attachment

Castrogiovanni, Cédric; Meraldi, Patrick

doi:10.1016/j.cub.2022.05.045

Scientific article

Comment

English

Cell division: the science friction of chromosome attachment

ContributorsCastrogiovanni, Cédric; Meraldi, Patrick

Published inCurrent biology, vol. 32, no. 13, p. R744-R746

Publication date2022-07-11

Abstract

During mitosis, chromosomes must bind spindle microtubules via kinetochores in a stable yet dynamic manner to ensure rapid frictionless movements. A recent study identifies the first complex that specifically reduces friction in the kinetochore-microtubule interface to ensure efficient chromosome segregation.

Keywords

Chromosome Segregation
Friction
Kinetochores
Microtubules / metabolism
Mitosis

Affiliation entities

Faculté de médecine / Section de médecine fondamentale / Département de physiologie cellulaire et métabolisme

Research groups

Groupe Meraldi Patrick (physiologie cellulaire et métabolisme) (922)

Citation (ISO format)

CASTROGIOVANNI, Cédric, MERALDI, Patrick. Cell division: the science friction of chromosome attachment. In: Current biology, 2022, vol. 32, n° 13, p. R744–R746. doi: 10.1016/j.cub.2022.05.045

Article (Published version)

Identifiers

PID : unige:162497
DOI : 10.1016/j.cub.2022.05.045
PMID : 35820385

Journal ISSN0960-9822

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Cell division: the science friction of chromosome attachment

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