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Scientific article
Review
Open access
English

Antimicrobial prophylaxis and preemptive approaches for the prevention of infections in the stem cell transplant recipient, with analogies to the hematologic malignancy patient

Published inInfectious disease clinics of North America, vol. 33, no. 2, p. 361-380
Publication date2019-06
Abstract

Infectious complications represent one of the most common causes of morbidity and mortality in allogeneic hematopoietic cell transplant (HCT) recipients. Prophylactic and preemptive treatment strategies against bacterial, fungal, viral, and parasitic pathogens are routinely implemented during high-risk post-HCT periods at most transplant centers. The basic concepts and review of current guidelines of antibiotic prophylaxis and empirical/preemptive antibiotic treatment in allogeneic HCT recipients are reviewed in this article.

eng
Keywords
  • Antibiotic prophylaxis
  • Antibiotics
  • Empirical treatment
  • Hematopoietic cell transplantation
  • Infectious complications
  • Neutropenia
  • Preemptive treatment
  • Anti-Infective Agents / administration & dosage
  • Bacterial Infections / prevention & control
  • Chemoprevention
  • Clinical Trials as Topic
  • Hematologic Neoplasms / complications
  • Hematologic Neoplasms / microbiology
  • Hematopoietic Stem Cell Transplantation / adverse effects
  • Humans
  • Meta-Analysis as Topic
  • Mycoses / prevention & control
  • Neutropenia
  • Observational Studies as Topic
  • Virus Diseases / prevention & control
Citation (ISO format)
NEOFYTOS, Dionysios. Antimicrobial prophylaxis and preemptive approaches for the prevention of infections in the stem cell transplant recipient, with analogies to the hematologic malignancy patient. In: Infectious disease clinics of North America, 2019, vol. 33, n° 2, p. 361–380. doi: 10.1016/j.idc.2019.02.002
Main files (2)
Article (Published version)
accessLevelRestricted
Article (Accepted version)
Identifiers
ISSN of the journal0891-5520
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