Synthesis, antiviral and antiproliferative activity of nucleoside-3'-<i>C</i>-acetamides and nucleoside-3'-<i>C</i>-acetamide oximes

Tronchet, Jean Marcel Julien; Grand, Eric; Flores, Imber Franz; Criton, Marc; Seman, Michel; Dilda, Pierre

Scientific article

English

Synthesis, antiviral and antiproliferative activity of nucleoside-3'-C-acetamides and nucleoside-3'-C-acetamide oximes

ContributorsTronchet, Jean Marcel Julien; Grand, Eric; Flores, Imber Franz; Criton, Marc; Seman, Michel; Dilda, Pierre

Published inCarbohydrate letters, vol. 3, no. 3, p. 203-210

Publication date1998

Abstract

Reduction of 3'-deoxy-3'-methoxycarbonylmethylene or 3'-cyanomethylene-3'-deoxynucleosides followed by ammonolysis or hydroxyaminolysis led respectively to the corresponding nucleoside-3'-C-acetamides or nucleoside-3'-C-acetamide oximes. Some of these novel nucleosides exhibited antiviral or antiproliferative activity.

Keywords

Branched-chain nucleosides
Antiviral
Antiproliferative
Amide oximes
Amides

Affiliation entities

Faculté des sciences / Section des sciences pharmaceutiques

Citation (ISO format)

TRONCHET, Jean Marcel Julien et al. Synthesis, antiviral and antiproliferative activity of nucleoside-3′-C-acetamides and nucleoside-3′-C-acetamide oximes. In: Carbohydrate letters, 1998, vol. 3, n° 3, p. 203–210.

Article (Published version)

Identifiers

PID : unige:161703

Journal ISSN1029-2438

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Synthesis, antiviral and antiproliferative activity of nucleoside-3'-C-acetamides and nucleoside-3'-C-acetamide oximes

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