en
Scientific article
Open access
French

Chirurgie du cancer pulmonaire à petites cellules de stade précoce: doit-on réévaluer son rôle?

Other title[The role of surgery in early stage small cell lung cancer: should it be re-evaluated?]
Published inRevue médicale suisse, vol. 9, no. 407, p. 2170,2172-2174
Publication date2013-11-20
Abstract

Two historical randomized controlled trials have demonstrated that chemo-radiotherapy offers the best survival advantage over surgery in small cell lung carcinoma (SCLC) and led to abandon surgery for the treatment of SCLC. Yet, widespread use of CT scanning increases the detection of early and very early stage SCLC. Therefore, the traditional 2 stages classification scheme--namely limited and extensive stage disease--is no longer sufficient for such early stage disease and must be completed by the TNM classification. Although randomized controlled trials are lacking, retrospective case series and large population databases suggest a beneficial role of surgery for the earliest SCLC stages. It is thus currently recommended to consider surgery in the multimodal treatment of stage I SCLC.

eng
Keywords
  • Chemoradiotherapy / methods
  • Combined Modality Therapy
  • Early Detection of Cancer
  • Humans
  • Lung Neoplasms / pathology
  • Lung Neoplasms / surgery
  • Lung Neoplasms / therapy
  • Neoplasm Staging
  • Randomized Controlled Trials as Topic
  • Small Cell Lung Carcinoma / pathology
  • Small Cell Lung Carcinoma / surgery
  • Small Cell Lung Carcinoma / therapy
  • Survival Rate
  • Tomography, X-Ray Computed / methods
Citation (ISO format)
CLEMENTE, M et al. Chirurgie du cancer pulmonaire à petites cellules de stade précoce: doit-on réévaluer son rôle? In: Revue médicale suisse, 2013, vol. 9, n° 407, p. 2170,2172–2174.
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Article (Published version)
accessLevelPublic
Identifiers
ISSN of the journal1660-9379
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