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Phagocytosis of chromium during patellar osteoarthritic remodelling associated with a knee prosthesis

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Published in Virchows Archiv. A. Pathological anatomy and histology. 1979, vol. 382, no. 1, p. 119-126
Abstract The report is of an anatomico-pathological and electron probe microanalyzer study of a patella with osteoarthritic remodelling, that had been in contact with a cast cobalt-chromium-molybdenum prosthesis for two years and seven months. Abrasion of the metal resulted in preferential phagocytosis of chromium, principally in the wall of an osteoarthritis cyst. This observation indicates that a substance administered by intra-articular pathway for the treatment of osteoarthritis can become phagocytosed, and quite deeply, in the remodelled bone.
Keywords OsteoarthritisJoint prosthesisMetal phagocytosisChromium
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PMID: 157595
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LAGIER, René, BERTRAND, Jean. Phagocytosis of chromium during patellar osteoarthritic remodelling associated with a knee prosthesis. In: Virchows Archiv. A. Pathological anatomy and histology, 1979, vol. 382, n° 1, p. 119-126. doi: 10.1007/BF01102746 https://archive-ouverte.unige.ch/unige:160022

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Deposited on : 2022-04-01

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