Scientific article
Open access

Cellulite non infectieuse à connaître: le syndrome de Wells

Other titleA non-infectious cellulitis to know: Wells' syndrome
Published inRevue médicale suisse, vol. 17, no. 732, p. 610-614
Publication date2021-03-31

Wells' syndrome is a rare inflammatory eosinophilic dermatosis. It typically appears as a sudden-onset of one or multiple inflammatory plaques associated with a pruritus. General symptoms are rare. There is often blood eosinophilia and a marked dermal eosinophilic infiltrate with flame figures on skin biopsy. Numerous trigger factors and associated diseases are described. The etiology is unclear. Most experts believe it to be a type IV hypersensitivity reaction in predisposed individuals with an imbalance TH1/TH2 cells. Circulating TH2 cells may be implicated by producing IL- 5 which stimulates eosinophils' degranulation. The aim of this article is to review the diagnostic and therapeutic options of this pathology knowing that the main differential diagnosis is cellulitis of infectious origin.

  • Cellulitis / diagnosis
  • Cellulitis / etiology
  • Eosinophilia / diagnosis
  • Eosinophilia / etiology
  • Humans
  • Skin
  • Syndrome
Citation (ISO format)
ALVAREZ MARTINEZ, David, LAFFITTE, Emmanuel Alexis. Cellulite non infectieuse à connaître: le syndrome de Wells. In: Revue médicale suisse, 2021, vol. 17, n° 732, p. 610–614.
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Article (Published version)
ISSN of the journal1660-9379

Technical informations

Creation03/11/2022 1:37:00 PM
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