Scientific article
Case report

Encephalopathy with epileptic spasms resolved with corticoids in a 69 year-old patient

Published inEpileptic disorders, vol. 2, no. 2, p. 123-125
Publication date2000-06

A 69 year-old man with a history of recent temporal lobe seizures, presented with progressive coma and frequent epileptic spasms. Ictal EEG, PET and SPECT alterations were strikingly similar to those described in infantile spasms. Conventional antiepileptic drugs were ineffective but the introduction of corticoids induced a dramatic improvement with disappearance of the spasms. The etiology remains unknown. Epileptic spasms may occur in the elderly. If conventional antiepileptic drugs are ineffective, corticoids should be tried immediately.

  • Aged
  • Anti-Inflammatory Agents / administration & dosage
  • Anti-Inflammatory Agents / therapeutic use
  • Anticonvulsants / therapeutic use
  • Brain / diagnostic imaging
  • Brain / metabolism
  • Brain / pathology
  • Drug Therapy, Combination
  • Electroencephalography
  • Epilepsy, Temporal Lobe / diagnosis
  • Epilepsy, Temporal Lobe / drug therapy
  • Humans
  • Magnetic Resonance Imaging
  • Male
  • Methylprednisolone / administration & dosage
  • Methylprednisolone / therapeutic use
  • Prednisolone / administration & dosage
  • Prednisolone / therapeutic use
  • Tomography, Emission-Computed
  • Tomography, Emission-Computed, Single-Photon
  • Treatment Outcome
  • Valproic Acid / therapeutic use
Citation (ISO format)
MATON, Bruno et al. Encephalopathy with epileptic spasms resolved with corticoids in a 69 year-old patient. In: Epileptic disorders, 2000, vol. 2, n° 2, p. 123–125.
Main files (1)
Article (Published version)
ISSN of the journal1294-9361

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