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Distribution of Aspergillus Species and Prevalence of Azole Resistance in Respiratory Samples From Swiss Tertiary Care Hospitals

Published inOpen forum infectious diseases, vol. 9, no. 2, ofab638
Publication date2022-02
First online date2021-12-18
Abstract

Among 400 Aspergillus species from respiratory samples in Switzerland, Aspergillus fumigatus was the most frequent species. Non-fumigatus Aspergillus spp were more prevalent among solid organ transplant recipients and after azole exposure. Azole resistance was detected in 4 A fumigatus isolates, 3 of them with the "environmental" mutation TR34/L98H in the cyp51A gene.

eng
Keywords
  • Aspergillus fumigatus
  • TR34/L98H mutation
  • Azole resistance
  • Cyp51A gene
  • Non-fumigatus Aspergillus spp
Citation (ISO format)
RAGOZZINO, Silvio et al. Distribution of Aspergillus Species and Prevalence of Azole Resistance in Respiratory Samples From Swiss Tertiary Care Hospitals. In: Open forum infectious diseases, 2022, vol. 9, n° 2, p. ofab638. doi: 10.1093/ofid/ofab638
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ISSN of the journal2328-8957
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Creation03/01/2022 1:10:00 PM
First validation03/01/2022 1:10:00 PM
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