Scientific article
Open access

COVID-19 in children and adolescents in Europe: a multinational, multicentre cohort study

Published inThe Lancet. Child & adolescent health., vol. 4, no. 9, p. 653-661
Publication date2020-09
First online date2020-06-25

Background: To date, few data on paediatric COVID-19 have been published, and most reports originate from China. This study aimed to capture key data on children and adolescents with severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection across Europe to inform physicians and health-care service planning during the ongoing pandemic. Methods: This multicentre cohort study involved 82 participating health-care institutions across 25 European countries, using a well established research network-the Paediatric Tuberculosis Network European Trials Group (ptbnet)-that mainly comprises paediatric infectious diseases specialists and paediatric pulmonologists. We included all individuals aged 18 years or younger with confirmed SARS-CoV-2 infection, detected at any anatomical site by RT-PCR, between April 1 and April 24, 2020, during the initial peak of the European COVID-19 pandemic. We explored factors associated with need for intensive care unit (ICU) admission and initiation of drug treatment for COVID-19 using univariable analysis, and applied multivariable logistic regression with backwards stepwise analysis to further explore those factors significantly associated with ICU admission.

  • Betacoronavirus
  • COVID-19
  • Child
  • Child, Preschool
  • Coronavirus Infections / epidemiology
  • Coronavirus Infections / therapy
  • Delivery of Health Care / organization & administration
  • Europe / epidemiology
  • Female
  • Follow-Up Studies
  • Humans
  • Infant
  • Infant, Newborn
  • Intensive Care Units / organization & administration
  • Male
  • Pandemics
  • Patient Admission / trends
  • Pneumonia, Viral / epidemiology
  • Pneumonia, Viral / therapy
  • Risk Factors
  • SARS-CoV-2
Citation (ISO format)
GÖTZINGER, Florian et al. COVID-19 in children and adolescents in Europe: a multinational, multicentre cohort study. In: The Lancet. Child & adolescent health., 2020, vol. 4, n° 9, p. 653–661. doi: 10.1016/S2352-4642(20)30177-2
Main files (1)
Article (Published version)
Secondary files (1)
ISSN of the journal2352-4642

Technical informations

Creation10/08/2021 7:58:00 AM
First validation10/08/2021 7:58:00 AM
Update time03/16/2023 2:42:29 AM
Status update03/16/2023 2:42:26 AM
Last indexation08/31/2023 7:45:46 AM
All rights reserved by Archive ouverte UNIGE and the University of GenevaunigeBlack