en
Scientific article
English

Trajectory of disability and quality-of-life in non-geriatric and geriatric survivors after severe traumatic brain injury

Published inBrain injury, vol. 31, no. 3, p. 319-328
Publication date2017
First online date2017-01-23
Abstract

Objective: The objective was to investigate disability and health-related quality-of-life (HRQoL) 3, 6 and 12 months after traumatic brain injury (TBI) in non-geriatric (≤ 65 years) and geriatric patients (> 65 years).

Methods: Patients ≥ 16 years who sustained a severe TBI (Abbreviated Injury Scale of the head region > 3) were included in this prospective, multi-centre study. Outcome measures were Glasgow Outcome Scale Extended (GOSE; disability), SF-12 (HRQoL). Mixed linear model analyses were performed.

Results: Three hundred and fifty-one patients (median age = 50 years; interquartile range (IQR) = 27-67) were included; 73.2% were male and 27.6% were geriatric patients. Median GOSE at 3, 6 and 12 months was 5 (IQR = 3-7), 6 (IQR = 4-8) and 7 (IQR = 5-8); this increase (slopetime = 0.22, p < 0.0001) was age dependent (slopeage*time = -0.06, p = 0.003). Median SF-12 physical component scale score at 3, 6 and 12 months was 42.1 (IQR = 33.6-50.7), 46.6 (IQR = 37.4-53.9) and 50.4 (IQR = 39.2-55.1); this increase (slopetime = 1.52, p < 0.0001) was not age dependent (slopeage*time = -0.30, p = 0.083). SF-12 mental component scale scores were unchanged.

Conclusions: Disability decreased and HRQoL improved after TBI between 3-12 months. In geriatric patients this improvement was relevant for HRQoL only.

eng
Keywords
  • Head injury
  • Elderly
  • Functional outcome
  • Health-related quality-of-life
  • Recovery
Citation (ISO format)
HALLER, Chiara S. et al. Trajectory of disability and quality-of-life in non-geriatric and geriatric survivors after severe traumatic brain injury. In: Brain injury, 2017, vol. 31, n° 3, p. 319–328. doi: 10.1080/02699052.2016.1255777
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Article (Published version)
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ISSN of the journal0269-9052
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