Scientific article
Open access

Pseudomalignancies in Children: Histological Clues, and Pitfalls to Be Avoided

Published inDermatopathology, vol. 8, no. 3, p. 376-389
Publication date2021-08-14
First online date2021-08-14

The term "pseudomalignancy" covers a large, heterogenous group of diseases characterized by a benign cellular proliferation, hyperplasia, or infiltrate that resembles a true malignancy clinically or histologically. Here, we (i) provide a non-exhaustive review of several inflammatory skin diseases and benign skin proliferations that can mimic a malignant neoplasm in children, (ii) give pathologists some helpful clues to guide their diagnosis, and (iii) highlight pitfalls to be avoided. The observation of clinical-pathological correlations is often important in this situation and can sometimes be the only means (along with careful monitoring of the disease's clinical course) of reaching a firm diagnosis.

  • CD1a+ dendritic cell hyperplasia
  • Spitz tumor
  • Acral pseudo-lymphomatous angiokeratoma of children
  • Congenital melanocytic lesion
  • Histiocytic infiltrate
  • Langerhans cell histiocytosis
  • Lymphomatoid papulosis
  • Lymphoplasmacytic plaque
  • Melanocytic disorders
  • Mycosis fungoides
  • Pediatrics
  • Pityriasis lichenoides
  • Proliferative nodule
  • Pseudolymphoma
  • Pseudomalignancies
Citation (ISO format)
MENZINGER, Sébastien, FRAITAG, Sylvie. Pseudomalignancies in Children: Histological Clues, and Pitfalls to Be Avoided. In: Dermatopathology, 2021, vol. 8, n° 3, p. 376–389. doi: 10.3390/dermatopathology8030042
Main files (1)
Article (Published version)
ISSN of the journal2296-3529

Technical informations

Creation01/21/2022 9:30:00 AM
First validation01/21/2022 9:30:00 AM
Update time03/16/2023 2:28:16 AM
Status update03/16/2023 2:28:15 AM
Last indexation05/06/2024 8:56:07 AM
All rights reserved by Archive ouverte UNIGE and the University of GenevaunigeBlack