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Scientific article
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Open access
English

Pseudomalignancies in Children: Histological Clues, and Pitfalls to Be Avoided

Published inDermatopathology, vol. 8, no. 3, p. 376-389
Publication date2021-08-14
First online date2021-08-14
Abstract

The term "pseudomalignancy" covers a large, heterogenous group of diseases characterized by a benign cellular proliferation, hyperplasia, or infiltrate that resembles a true malignancy clinically or histologically. Here, we (i) provide a non-exhaustive review of several inflammatory skin diseases and benign skin proliferations that can mimic a malignant neoplasm in children, (ii) give pathologists some helpful clues to guide their diagnosis, and (iii) highlight pitfalls to be avoided. The observation of clinical-pathological correlations is often important in this situation and can sometimes be the only means (along with careful monitoring of the disease's clinical course) of reaching a firm diagnosis.

eng
Keywords
  • CD1a+ dendritic cell hyperplasia
  • Spitz tumor
  • Acral pseudo-lymphomatous angiokeratoma of children
  • Congenital melanocytic lesion
  • Histiocytic infiltrate
  • Langerhans cell histiocytosis
  • Lymphomatoid papulosis
  • Lymphoplasmacytic plaque
  • Melanocytic disorders
  • Mycosis fungoides
  • Pediatrics
  • Pityriasis lichenoides
  • Proliferative nodule
  • Pseudolymphoma
  • Pseudomalignancies
Citation (ISO format)
MENZINGER, Sébastien, FRAITAG, Sylvie. Pseudomalignancies in Children: Histological Clues, and Pitfalls to Be Avoided. In: Dermatopathology, 2021, vol. 8, n° 3, p. 376–389. doi: 10.3390/dermatopathology8030042
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ISSN of the journal2296-3529
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