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Scientific article
Open access
English

MGMT methylation may benefit overall survival in patients with moderately vascularized glioblastomas

Published inEuropean Radiology, vol. 31, no. 3, p. 1738-1747
Publication date2021
Abstract

To assess the combined role of tumor vascularity, estimated from perfusion MRI, and MGMT methylation status on overall survival (OS) in patients with glioblastoma.

Keywords
  • Antineoplastic Agents
  • Alkylating/therapeutic use
  • Brain Neoplasms/diagnostic imaging/drug therapy/genetics
  • DNA Methylation
  • DNA Modification Methylases/genetics
  • DNA Repair Enzymes/genetics
  • Glioblastoma/diagnostic imaging/genetics
  • Humans
  • Prognosis
  • Promoter Regions
  • Genetic
  • Temozolomide/therapeutic use
  • Tumor Suppressor Proteins/genetics
Funding
  • European Commission - 727560, 825750, 758657
  • European Commission - 844646
Citation (ISO format)
FUSTER-GARCIA, Elies et al. MGMT methylation may benefit overall survival in patients with moderately vascularized glioblastomas. In: European Radiology, 2021, vol. 31, n° 3, p. 1738–1747. doi: 10.1007/s00330-020-07297-4
Main files (1)
Article (Published version)
Identifiers
ISSN of the journal0938-7994
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51downloads

Technical informations

Creation10/19/2021 10:26:00 AM
First validation10/19/2021 10:26:00 AM
Update time03/16/2023 2:25:53 AM
Status update03/16/2023 2:25:52 AM
Last indexation02/12/2024 12:18:37 PM
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