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Scientific article
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English

The impact of EPI-based distortion correction of dynamic susceptibility contrast MRI on cerebral blood volume estimation in patients with glioblastoma

Published inEuropean Journal of Radiology, vol. 132, 109278
Publication date2020
Abstract

Relative cerebral blood volume (rCBV) from dynamic susceptibility contrast (DSC)-MRI is a valuable biomarker in patients with glioblastoma for assessing treatment response and predicting overall survival. DSC-MRI based on echo planar images (EPI) may possess severe geometric distortions from magnetic field inhomogeneities up to the order of centimeters. The aim of this study is to assess how much two readily available EPI-based geometric distortion correction methods, FSL TOPUP and EPIC, affect rCBV values from DSC-MRI in patients with confirmed glioblastoma.

Keywords
  • Brain
  • Brain Neoplasms/diagnostic imaging
  • Cerebral Blood Volume
  • Contrast Media
  • Echo-Planar Imaging
  • Glioblastoma/diagnostic imaging
  • Humans
  • Magnetic Resonance Imaging
Citation (ISO format)
HOVDEN, Ivar T et al. The impact of EPI-based distortion correction of dynamic susceptibility contrast MRI on cerebral blood volume estimation in patients with glioblastoma. In: European Journal of Radiology, 2020, vol. 132, p. 109278. doi: 10.1016/j.ejrad.2020.109278
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Identifiers
ISSN of the journal0720-048X
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Technical informations

Creation10/17/2021 7:29:00 PM
First validation10/17/2021 7:29:00 PM
Update time03/16/2023 2:24:27 AM
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