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Scientific article
Open access
English

Incorporating variability of patient inflow conditions into statistical models for aneurysm rupture assessment

Published inActa Neurochirurgica, vol. 162, no. 3, p. 553-566
Publication date2020
Abstract

Hemodynamic patterns have been associated with cerebral aneurysm instability. For patient-specific computational fluid dynamics (CFD) simulations, the inflow rates of a patient are typically not known. The aim of this study was to analyze the influence of inter- and intra-patient variations of cerebral blood flow on the computed hemodynamics through CFD simulations and to incorporate these variations into statistical models for aneurysm rupture prediction.

Keywords
  • Aneurysm, Ruptured/diagnosis
  • Biological Variation, Population
  • Cerebrovascular Circulation
  • Female
  • Hemodynamics
  • Humans
  • Intracranial Aneurysm/diagnosis
  • Male
  • Middle Aged
  • Patient-Specific Modeling
Funding
  • Autre - SystemsX.ch project AneuX evaluated by the Swiss National Science Foundation
  • Autre - National Institutes of Neurological Disorders and Stroke (NIH-NINDS), Grant No. R01NS097457.
Citation (ISO format)
DETMER, Felicitas J et al. Incorporating variability of patient inflow conditions into statistical models for aneurysm rupture assessment. In: Acta Neurochirurgica, 2020, vol. 162, n° 3, p. 553–566. doi: 10.1007/s00701-020-04234-8
Main files (2)
Article (Published version)
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Article (Accepted version)
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Secondary files (1)
Identifiers
ISSN of the journal0001-6268
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Technical informations

Creation10/10/2021 7:14:00 PM
First validation10/10/2021 7:14:00 PM
Update time03/16/2023 2:24:23 AM
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