Scientific article
English

Seizure outcome and use of antiepileptic drugs after epilepsy surgery according to histopathological diagnosis: a retrospective multicentre cohort study

ContributorsLamberink, Herm J; Otte, Willem M; Blümcke, Ingmar; Braun, Kees P J; European Reference Network EpiCARE study group; European Epilepsy Brain Bank writing group
Published inLancet neurology, vol. 19, no. 9, p. 748-757
Publication date2020
Abstract

Surgery is a widely accepted treatment option for drug-resistant focal epilepsy. A detailed analysis of longitudinal postoperative seizure outcomes and use of antiepileptic drugs for different brain lesions causing epilepsy is not available. We aimed to analyse the association between histopathology and seizure outcome and drug freedom up to 5 years after epilepsy surgery, to improve presurgical decision making and counselling.

Keywords
  • Adolescent
  • Adult
  • Aged
  • Anticonvulsants/therapeutic use
  • Child
  • Child
  • Preschool
  • Cohort Studies
  • Drug Resistant Epilepsy/drug therapy/pathology/surgery
  • Female
  • Humans
  • Infant
  • Longitudinal Studies
  • Male
  • Middle Aged
  • Retrospective Studies
  • Seizures/drug therapy/pathology/prevention & control
  • Treatment Outcome
  • Young Adult
Citation (ISO format)
LAMBERINK, Herm J et al. Seizure outcome and use of antiepileptic drugs after epilepsy surgery according to histopathological diagnosis: a retrospective multicentre cohort study. In: Lancet neurology, 2020, vol. 19, n° 9, p. 748–757. doi: 10.1016/S1474-4422(20)30220-9
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Article (Published version)
accessLevelRestricted
Identifiers
Journal ISSN1474-4422
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