Randomized clinical trials in ANCA-associated vasculitis: a systematic analysis of the WHO - International Clinical Trials Registry Platform

Iudici, Michele; Puéchal, Xavier; Brigante, Alejandro; Atal, Ignacio; Gabay, Cem

doi:10.1186/s13023-020-01408-6

Scientific article

English

Randomized clinical trials in ANCA-associated vasculitis: a systematic analysis of the WHO - International Clinical Trials Registry Platform

ContributorsIudici, Michele

; Puéchal, Xavier; Brigante, Alejandro; Atal, Ignacio; Gabay, Cem

Published inOrphanet Journal of Rare Diseases, vol. 15, no. 1, 130

Publication date2020

Abstract

The analysis of the main features of randomized controlled trials (RCTs) on ANCA-associated vasculitis (AAV) can inform future study design. We searched within the International Clinical Trials Registry Platform all registered RCTs on AAV from October 2008 to December 2018. Two reviewers selected studies according to pre-specified eligibility criteria. We retrieved information including countries, funding, design, sample sizes, eligibility criteria, primary outcomes (POs), and treatments.

Keywords

Anti-Neutrophil Cytoplasmic Antibody-Associated Vasculitis/drug therapy
Europe
Humans
Randomized Controlled Trials as Topic
Registries
World Health Organization

Affiliation entities

Faculté de médecine / Section de médecine clinique / Département de médecine

Research groups

Inflammation articulaire (44)

Citation (ISO format)

IUDICI, Michele et al. Randomized clinical trials in ANCA-associated vasculitis: a systematic analysis of the WHO - International Clinical Trials Registry Platform. In: Orphanet Journal of Rare Diseases, 2020, vol. 15, n° 1, p. 130. doi: 10.1186/s13023-020-01408-6