Incidence of hepatocellular carcinoma in patients with nonalcoholic fatty liver disease: a systematic review, meta-analysis, and meta-regression

Orci, Lorenzo; Sanduzzi-Zamparelli, Marco; Caballol, Berta; Sapena, Victor; Colucci, Nicola; Torres, Ferran; Bruix, Jordi; Reig, María; Toso, Christian

doi:10.1016/j.cgh.2021.05.002

Scientific article

Review

English

Incidence of hepatocellular carcinoma in patients with nonalcoholic fatty liver disease: a systematic review, meta-analysis, and meta-regression

ContributorsOrci, Lorenzo; Sanduzzi-Zamparelli, Marco; Caballol, Berta; Sapena, Victor; Colucci, Nicola; Torres, Ferran; Bruix, Jordi; Reig, María; Toso, Christian

Published inClinical Gastroenterology and Hepatology

Publication date2021

Abstract

Nonalcoholic fatty liver disease (NAFLD) may be a risk factor for hepatocellular carcinoma (HCC), but the extent of this association still needs to be addressed. Pooled incidence rates of HCC across the disease spectrum of NAFLD have never been estimated by meta-analysis.

Keywords

Hepatocellular Carcinoma
Incidence
Meta-analysis
Nonalcoholic Fatty Liver Disease

Affiliation entities

Research groups

Transplantation et hépatologie (905)

Funding

Citation (ISO format)

ORCI, Lorenzo et al. Incidence of hepatocellular carcinoma in patients with nonalcoholic fatty liver disease: a systematic review, meta-analysis, and meta-regression. In: Clinical Gastroenterology and Hepatology, 2021. doi: 10.1016/j.cgh.2021.05.002

Article (Published version)

Identifiers

PID : unige:157504
DOI : 10.1016/j.cgh.2021.05.002
PMID : 33965578

Journal ISSN1542-3565

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Creation02/06/2021 14:27:00

First validation02/06/2021 14:27:00

Update13/10/2025 15:45:57

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Incidence of hepatocellular carcinoma in patients with nonalcoholic fatty liver disease: a systematic review, meta-analysis, and meta-regression

Nonalcoholic fatty liver disease (NAFLD) may be a risk factor for hepatocellular carcinoma (HCC), but the extent of this association still needs to be addressed. Pooled incidence rates of HCC across the disease spectrum of NAFLD have never been estimated by meta-analysis.

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