Supplemental parenteral nutrition improves immunity with unchanged carbohydrate and protein metabolism in critically ill patients: The SPN2 randomized tracer study

Berger, Mette M.; Pantet, Olivier; Jacquelin-Ravel, Nathalie; Charrière, Mélanie; Schmidt, Sabine; Becce, Fabio; Audran, Régine; Spertini, François; Tappy, Luc; Pichard, Claude

doi:10.1016/j.clnu.2018.10.023

Scientific article

English

Supplemental parenteral nutrition improves immunity with unchanged carbohydrate and protein metabolism in critically ill patients: The SPN2 randomized tracer study

ContributorsBerger, Mette M.; Pantet, Olivier; Jacquelin-Ravel, Nathalie; Charrière, Mélanie; Schmidt, Sabine; Becce, Fabio; Audran, Régine; Spertini, François; Tappy, Luc; Pichard, Claude

Published inClinical Nutrition, vol. 38, no. 5, p. 2408-2416

Publication date2019

Abstract

Individualized supplemental parenteral nutrition (SPN) providing measured energy expenditure from day 4 reduced infectious complications in a previous study including 305 intensive care (ICU) patients. The study aimed at investigating the metabolic, and immune responses underlying the clinical response of the previous trial.

Keywords

Critical illness
Immune response
Protein turnover
Glucose kinetics
Muscle mass
Infection

Affiliation

Faculté de médecine / Section de médecine clinique / Département de médecine

Citation (ISO format)

BERGER, Mette M. et al. Supplemental parenteral nutrition improves immunity with unchanged carbohydrate and protein metabolism in critically ill patients: The SPN2 randomized tracer study. In: Clinical Nutrition, 2019, vol. 38, n° 5, p. 2408–2416. doi: 10.1016/j.clnu.2018.10.023

Article (Published version)

Identifiers

PID : unige:157421
DOI : 10.1016/j.clnu.2018.10.023
PMID : 30448193

Commercial URLhttps://linkinghub.elsevier.com/retrieve/pii/S0261561418325184

ISSN of the journal0261-5614

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Creation07/27/2021 3:09:00 PM

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Supplemental parenteral nutrition improves immunity with unchanged carbohydrate and protein metabolism in critically ill patients: The SPN2 randomized tracer study

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